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Drug-Drug Interactions for Therapeutic Biologics (in English)
Honghui Zhou; Bernd Meibohm
Synopsis "Drug-Drug Interactions for Therapeutic Biologics (in English)"
Strategize, plan, and execute comprehensive drug-druginteraction assessments for therapeutic biologicsOffering both theory and practical guidance, this book fullyexplores drug-drug interaction assessments for therapeuticbiologics during the drug development process. It draws togetherand analyzes all the latest findings and practices in order topresent our current understanding of the topic and point the way tonew research. Case studies and examples, coupled with expertadvice, enable readers to better understand the complex mechanismsof biologic drug-drug interactions.Drug-Drug Interactions for Therapeutic Biologics featurescontributions from leading international experts in all areas oftherapeutic biologics drug development and drug-drug interactions.The authors' contributions reflect a thorough review and analysisof the literature as well as their own firsthand laboratoryexperience. Coverage includes such essential topics as:Drug-drug interaction risks in combination with small moleculesand other biologicsPharmacokinetic and pharmacodynamic drug-drug interactionsIn vitro methods for drug-drug interaction assessment andpredictionRisk-based strategies for evaluating biologic drug-druginteractionsStrategies to minimize drug-drug interaction risk and mitigatetoxic interactionsKey regulations governing drug-drug interaction assessments fortherapeutic biologics.Drug-Drug Interactions for Therapeutic Biologics isrecommended for pharmaceutical and biotechnology scientists,clinical pharmacologists, medicinal chemists, and toxicologists. Byenabling these readers to understand how therapeutic biologics mayinteract with other drugs, the book will help them develop safer,more effective therapeutic biologics.
