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portada Ubiquitin Family Modifiers and the Proteasome: Reviews and Protocols (Methods in Molecular Biology, 832) (in English)
Type
Physical Book
Publisher
Language
English
Pages
682
Format
Paperback
ISBN13
9781493959051
Edition No.
1

Ubiquitin Family Modifiers and the Proteasome: Reviews and Protocols (Methods in Molecular Biology, 832) (in English)

Dohmen R. Jürgen|Scheffner Martin (Author) · Humana · Paperback

Ubiquitin Family Modifiers and the Proteasome: Reviews and Protocols (Methods in Molecular Biology, 832) (in English) - Dohmen R. Jürgen|Scheffner Martin

Physical Book

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Synopsis "Ubiquitin Family Modifiers and the Proteasome: Reviews and Protocols (Methods in Molecular Biology, 832) (in English)"

The ubiquitin-proteasome system (UPS) and ubiquitin-related modifiers are not only involved in cellular protein quality control but also in the regulation of many fundamental cellular processes/pathways as well as in their disease-relevant aberrations. Ubiquitin Family Modifiers and Proteasome: Reviews and Protocols presents both novel developments in UPS research and important methods related to the main recent advances in the field of ubiquitin family modifiers. Divided into five convenient sections, this volume focuses on the enzymology and substrate identification of ubiquitin family modifiers, the recognition and chain formation of these modifiers, the analysis of proteasome biogenesis and function, protein quality control, and finally the use of small molecules and strategies to study or manipulate the function of the UPS and of ubiquitin family modifiers, respectively. Written in the highly successful Methods in Molecular Biology(TM) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Ubiquitin Family Modifiers and Proteasome: Reviews and Protocols will be of great use to investigators and students engaged in both basic and applied research in life sciences.

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The book is written in English.
The binding of this edition is Paperback.

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