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portada cell death signaling in cancer biology and treatment (in English)
Type
Physical Book
Illustrated by
Publisher
Year
2012
Language
English
Pages
408
Format
Hardcover
Dimensions
23.4 x 15.7 x 2.8 cm
Weight
0.77 kg.
ISBN
1461458463
ISBN13
9781461458463

cell death signaling in cancer biology and treatment (in English)

Daniel Johnson (Illustrated by) · Humana · Hardcover

cell death signaling in cancer biology and treatment (in English) - Johnson, Daniel

Physical Book

$ 161.04

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Synopsis "cell death signaling in cancer biology and treatment (in English)"

A key goal in the treatment of cancer is to achieve selective and efficient killing of tumor cells. The aim of Cell Death Signaling in Cancer Biology and Treatment is to describe state-of-the-art approaches and future opportunities for achieving this goal by targeting mechanisms and pathways that regulate cancer cell death. In this book, molecular defects in cell death signaling that characterize cancer cells, including dysregulation of cell death due to overexpression/hyperactivation of oncoproteins, as well as the loss of tumor suppressor proteins will be described. The potential for targeting microRNAs will be discussed. Multiple chapters will describe preclinical and clinical approaches that are currently being used to target epigenetic modifications, DNA repair pathways, and protein chaperones, as a means of provoking tumor cell death. Finally, the development and application of novel agents and approaches for targeting specific components of cell death signaling pathways and machinery will be reviewed.

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All books in our catalog are Original.
The book is written in English.
The binding of this edition is Hardcover.

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