Share
Development of a new Heterocycle-Forming Reaction and Kinetic Resolution With N-Heterocyclic Carbenes (Springer Theses) (in English)
Yinli Wang (Author)
·
Springer
· Hardcover
Development of a new Heterocycle-Forming Reaction and Kinetic Resolution With N-Heterocyclic Carbenes (Springer Theses) (in English) - Yinli Wang
$ 104.20
$ 109.99
You save: $ 5.79
Choose the list to add your product or create one New List
✓ Product added successfully to the Wishlist.
Go to My WishlistsIt will be shipped from our warehouse between
Monday, May 20 and
Tuesday, May 21.
You will receive it anywhere in United States between 1 and 3 business days after shipment.
Synopsis "Development of a new Heterocycle-Forming Reaction and Kinetic Resolution With N-Heterocyclic Carbenes (Springer Theses) (in English)"
In this book, the author focuses on exploring new organocatalytic transformations under operationally simple and environmentally friendly reaction conditions. Two new types of catalytic reactions promoted by N-heterocyclic carbenes (NHCs) are described. The oxa- and azacycle-forming reactions of sulfonylalkynols and sulfonylalkynamides are broadly considered to be a new type of activation mode in NHC chemistry, wherein the bond formation with internal O- and N-nucleophiles occurs at the γ-position of the propargyl sulfones with 1,2-sulfonyl migration. The resulting oxa- and azacycles are core structures in many biologically significant compounds and medicinally important agents. In addition, the book develops the chiral NHC-catalyzed kinetic resolution of α-hydroxy carboxylic acid derivatives based on chiral recognition of the substrate–cocatalyst complex. In this carboxylate cocatalyst-assisted chiral acylation, the reaction rate acceleration and selectivity enhancement are interpreted in terms of the reversible complexation of the substrate and carboxylate cocatalyst, which is verified by control experiments and measured using analytical methods. The findings described here reveal a promising new aspect of not only NHC catalysis but also identifying novel catalysis systems.
- 0% (0)
- 0% (0)
- 0% (0)
- 0% (0)
- 0% (0)
All books in our catalog are Original.
The book is written in English.
The binding of this edition is Hardcover.
✓ Producto agregado correctamente al carro, Ir a Pagar.