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Molecular Neurosurgery with Targeted Toxins (in English)
Wiley, Ronald G. ; Lappi, Douglas A. (Author)
·
Humana
· Paperback
Molecular Neurosurgery with Targeted Toxins (in English) - Wiley, Ronald G. ; Lappi, Douglas A.
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Origin: United Kingdom
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Synopsis "Molecular Neurosurgery with Targeted Toxins (in English)"
Pioneers and leading researchers explain the theory and techniques of using targeted toxins experimentally. The highly successful use of the 192 IgG-saporin and ME20.4-saporin immunotoxins to lesion the cholinergic basal forebrain in order to model the behavior, anatomy, physiology, and pharmacology of Alzheimer's disease in animals is treated in detail too give a potential user the knowledge to comfortably use the techniques involved. The uses of important new lesioning agents such as anti-DBH-saporin immunotoxin to make remarkably selective lesions of catecholaminergic neurons, hypocretin-saporin that can produce narcoleptic animals, and other saporin conjugates, such as neuropeptide-saporin conjugates for pain research and cholera toxin B chain-saporin to produce a model of CNS demyelination are explained by experts in the field.
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The book is written in English.
The binding of this edition is Paperback.
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