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protein quality control in neurodegenerative diseases (in English)
Yves Christen
(Illustrated by)
·
Richard I. Morimoto
(Illustrated by)
·
Springer
· Hardcover
protein quality control in neurodegenerative diseases (in English) - Morimoto, Richard I. ; Christen, Yves
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Synopsis "protein quality control in neurodegenerative diseases (in English)"
The health of the proteome depends upon protein quality control to regulate the proper synthesis, folding, translocation, and clearance of proteins. The cell is challenged constantly by environmental and physiological stress, aging, and the chronic expressions of disease associated misfolded proteins. Substantial evidence supports the hypothesis that the expression of damaged proteins initiates a cascade of molecular events that leads to Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, and other diseases of protein conformation.
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The book is written in English.
The binding of this edition is Hardcover.
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