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portada Rna Worlds: New Tools for Deep Exploration (in English)
Type
Physical Book
Publisher
Author
Year
2018
Language
English
Pages
580
Format
Hardcover
ISBN13
9781621822240
Categories

Rna Worlds: New Tools for Deep Exploration (in English)

Thomas R (Howard Hughes Medical Institute University Of Colorado Boulder) Cech; Joan A (Howard Hughes Medical Institute Yale University) Steitz; John F (The University Of Utah) Atkins (Author) · Cold Spring Harbor Laboratory Press · Hardcover

Rna Worlds: New Tools for Deep Exploration (in English) - Thomas R (Howard Hughes Medical Institute University Of Colorado Boulder) Cech; Joan A (Howard Hughes Medical Institute Yale University) Steitz; John F (The University Of Utah) Atkins

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Origin: United Kingdom (Import costs included in the price)
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Synopsis "Rna Worlds: New Tools for Deep Exploration (in English)"

RNA (ribonucleic acid) molecules drive much of cellular action. Messenger RNA (mRNA) relays genetic information from DNA to ribosomes to direct the formation of proteins. At the same time, noncoding RNAs act as enzymes, scaffolds, and regulatory molecules, contributing greatly to the regulation of gene activity, RNA splicing, protein synthesis, and even DNA replication.This new edition of the highly successful RNA Worlds series focuses on emerging tools for analysis of RNA biology and how these tools are driving our understanding of RNA structure and function. The contributors review new approaches for imaging RNA molecules in cells, techniques for analyzing the behavior of single RNA molecules in vitro and in vivo, transcriptome-wide analyses, and novel methods for determining the structure of RNA and RNP (ribonucleoprotein) complexes. They discuss the insights these provide into the transcription and splicing machinery, ribosomes, reverse transcriptases, and subcellular structures such as stress granules.Also included are chapters exploring CRISPR editing, RNA switches for use in synthetic biology, and development of novel drugs targeting pathogenic RNA structures. In addition, the book covers recent insights into the primordial RNA World, including protocells and homochirality. It will therefore be of interest not only to biochemists and molecular biologists but to evolutionary biologists pondering the emergence of life on Earth.

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