Share
Taurine 4: Taurine and Excitable Tissues (in English)
Della Corte, Laura ; Huxtable, Ryan J. ; Sgaragli, Giampietro (Author)
·
Springer
· Paperback
Taurine 4: Taurine and Excitable Tissues (in English) - Della Corte, Laura ; Huxtable, Ryan J. ; Sgaragli, Giampietro
$ 207.47
$ 219.00
You save: $ 11.53
Choose the list to add your product or create one New List
✓ Product added successfully to the Wishlist.
Go to My WishlistsIt will be shipped from our warehouse between
Monday, June 17 and
Tuesday, June 18.
You will receive it anywhere in United States between 1 and 3 business days after shipment.
Synopsis "Taurine 4: Taurine and Excitable Tissues (in English)"
Mitochondria from mammalian tissues possess an elaborate system for 2+ 2+ transporting Ca across their inner membrane which consists of Ca import, 2+ via the Ca uniporter, in response to the mitochondrial membrane 2+ + potential and of Ca release by an antiport system in exchange for H + 9,23 or Na (see Fig. l) . Because the uniporter is dependent upon the external 2+ 2+ 2+ 2+ Ca concentration ([Ca ]), mitochondria accumulate Ca until the [Ca ] o o 2+ decreases to the level at which the uniporter activity balances the Ca efflux. 2+ The [Ca ] at which the uniporter and efflux activities are equal is defined o the "setpoint" andcorresponds to values between 0.3-3 M. 2+ Figure 1. The Ca transport system of the inner membrane of mammalian mitochondria. U, + 2+ + + uniporter. I, Na -independent efflux mechanism or Ca /2H exchanger. D, Na -dependent 2+ + efflux mechanism or Ca /2Na exchanger. PTP, permeability transition pore. FP, 11 flavoprotein. membrane potential. ? pH gradient. Adapted from .